When it comes to dermal fillers, the amount of time it takes for them to dissolve varies depending on the area and the amount of filler used. Generally, it takes 48-72 hours for the filler to start breaking down, but it can take up to two weeks for the entire fill to completely dissolve and settle naturally. Most fillers settle down or show their full results after 2 to 3 weeks, although there are a few exceptions. It takes time for the filler to break down, integrate with the tissue in the surrounding area, and begin to moisturize the skin.
Hyaluronic acid fillers, such as Juvederm, are typically metabolized after 6 months to a year. However, if you need to dissolve them sooner, hyaluronidase enzyme can be used. This enzyme starts working almost immediately and can help dissolve the filler quickly.